Based on the lineups i saw here i'm not surprised they struggled.
https://twitter.com/stpatsfc/status/626462731479162880 Proper botch job team that. O'Brien barely played last year through injury and being not as good as Gunn. Of the starting XI i'd say only handful at best have a chance at City in the long term. The rest are decent, but its thrown together. Not seen Faupala so i cant comment. The bench is a lot stronger on paper. Bryan, Ambrose (when fit), Maffeo and Wood would probably all improve that team. Fernandes too - lovely little footballer. Technically excellent - just incredibly small.
From last year's EDS team there's Gunn, Humphreys, Garcia, Horsfield, Tosin, Angelino, Byrne, Ntcham, Barker, Iheanacho, Pozo, a fit Ambrose & Maffeo all notably missing. It's weakened basically and not even close to representative of the talent we've got coming through unfortunately for your viewing!
Edit - interesting to note that you mentioned Glendon and Fernandes as two positives, seeing as I would have picked the former as one of the ones most likely to look comfortable in that lineup. Fernandes too always looks good to me in every game I see.