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| Date | Opponents | Competition | Kick Off/City Scorers |
F-A | Crowd | |||
| Sun 13 Jul | A |  |
Dundee FC | Pre-Season Friendly |  |
0 – 2 | 6,859 | |
| Fri 18 Jul | A |  |
Hearts | Pre-Season Friendly | Sinclair (25) Kolarov (82pen) | |
2 – 1 | 12,118 |
| Wed 23 Jul | A |  |
Sporting Kansas City | Pre-Season Friendly | Zuculini (3) Boyata (45) Kolarov (72pen) Iheanacho (88) | |
4 – 1 | 18,484 |
| Sun 27 Jul | N |  |
AC Milan |  |
Jovetic (11) Sinclair (14) Navas (23) Iheanacho (26) Jovetic (58) | |
5 – 1 | 34,347 |
| Wed 30 Jul | N |  |
Liverpool | |
Jovetic (53) Jovetic (67) | |
2 – 2 | 49.653 |
| Sat 02 Aug | N |  |
Olympiacos | |
Jovetic (35) Kolarov (51pen) | |
2 – 2 | 30,000 |
| Sun 10 Aug |  |
 |
Arsenal |  |
|
0 – 3 | ||
| Sun 17 Aug | A |  |
Newcastle United |  |
Silva (37) Aguero (91) |  |
2 – 0 | 50,816 |
| Mon 25 Aug | H | |
Liverpool | |
Jovetic (41) Jovetic (55) Aguero (70) | |
3 – 1 | 45,471 |
| Sat 30 Aug | H |  |
Stoke City | |
|
0 – 1 | 45,622 | |
| Sat 13 Sept | A | |
Arsenal | |
Aguero (27) Demichelis (83) | |
2 – 2 | 60,000 |
| Wed 17 Sept | A |  |
Bayern Munich |  |
 |
0 – 1 | 62,000 | |
| Sun 21 Sept | H |  |
Chelsea | |
Lampard (85) | |
1 – 1 | 45,602 |
| Wed 24 Sept | H |  |
Sheffield Wednesday |  |
Lampard (47) Dzeko (53) Navas (54) Yaya Toure (60pen) Dzeko (77) Pozo (88) Lampard (90) |  |
7 – 0 | 32,346 |
| Sat 27 Sept | A |  |
Hull City | |
Aguero (7) Dzeko (10) Dzeko (67) Lampard (87) | |
4 – 2 | 25,000 |
| Tue 30 Sept | H |  |
AS Roma | |
Aguero (4pen) | |
1 – 1 | |
| Sat 04 Oct | A |  |
Aston Villa | |
Yaya Toure (82) Aguero (88) | |
2 – 0 | 32,964 |
| Sat 18 Oct |
H |  |
Tottenham Hotspur | |
Aguero (13pen) Aguero (20pen) Aguero (68) Aguero (75) | |
4 – 1 | 45,541 |
| Tue 21 Oct | A |  |
CSKA Moscow | |
Aguero (29) Milner (38) | |
2 – 2 | |
| Sat 25 Oct | A |  |
West Ham United | |
Silva (77) |  |
1 – 2 | |
| Wed 29 Oct | H | |
Newcastle United | |
|
0 – 2 | 40,752 | |
| Sun 02 Nov | H |  |
Manchester United | |
Aguero (62) | |
1 – 0 | 45,358 |
| Wed 5 Nov | H | |
CSKA Moscow | |
Yaya Toure (7) | |
1 – 2 | |
| Sat 08 Nov | A |  |
Queens Park Rangers | |
Aguero (32) Aguero (83) | |
2 – 2 | 25,000 |
| Sat 22 Nov | H |  |
Swansea City | |
Jovetic (18) Yaya Toure (62) | |
2 – 1 | 45,448 |
| Tue 25 Nov |
H | |
Bayern Munich | |
Aguero (21pen) Aguero (85) Aguero (91) | |
3 – 2 | 44,502 |
| Sun 30 Nov | A |  |
Southampton | |
Yaya Toure (51) Lampard (80) Clichy (87) | |
3 – 0 | |
| Wed 03 Dec | A |  |
Sunderland | |
Aguero (21) Jovetic (39) Zabaleta (55) Aguero (71) | |
4 – 1 | 41,152 |
| Sat 06 Dec | H |  |
Everton | |
Yaya Toure (23pen) | |
1 – 0 | 45,603 |
| Wed 10 Dec | A | |
AS Roma | |
Nasri (60) Zabaleta (86) | |
2 – 0 | 70,000 |
| Sat 13 Dec | A |  |
Leicester City | |
Lampard (39) | |
1 – 0 | 31,643 |
| Sat 20 Dec | H |  |
Crystal Palace | |
Silva (48) Silva (60) Yaya Toure (80) | |
3 – 0 | |
| Fri 26 Dec | A |  |
West Brom | |
Fernando (7) Yaya Toure (12pen) Silva (33) | |
3 – 1 | 26,040 |
| Sun 28 Dec | H |  |
Burnley | |
Silva (23) Fernandinho (33) | |
2 – 2 | 45,608 |
| Thu 01 Jan | H | |
Sunderland | |
Yaya Toure (57) Jovetic (66) Lampard (73) | |
3 – 2 | 45,367 |
| Jan | |
Sheffield Wednesday |  |
Milner (66) Milner (91) |  |
2 – 1 | 44,309 | |
| Sat 10 Jan | A | |
Everton | |
15:00 | |||
| Sun 18 Jan | H | |
Arsenal | |
16:00  |
|||
| Sat 24 Jan | H | Middlesbrough | |
15:00 | ||||
| Sat 31 Jan | A | |
Chelsea | |
17:30 |
|||
| Sat 07 Feb | H | |
Hull City | |
15:00 | |||
| Wed 11 Feb | A | |
Stoke City | |
20:00 | |||
| Sat 21 Feb | H | |
Newcastle United | |
17:30 |
|||
| Tue 24 Feb | H |  |
FC Barcelona | |
19:45  |
|||
| Sun 01 Mar | A | |
Liverpool | |
12:00 |
|||
| Wed 04 Mar | H | |
Leicester City | |
20:00 | |||
| Sat 14 Mar | A | |
Burnley | |
15:00 | |||
| Wed 18 Mar | A | |
FC Barcelona | |
19:45 |
|||
| Sat 21 Mar | H | |
West Brom | |
15:00 | |||
| Sat 04 Apr | A | |
Crystal Palace | |
15:00 | |||
| Sat 11 Apr | A | |
Manchester United | |
15:00 | |||
| Sat 18 Apr | H | |
West Ham United | |
15:00 | |||
| Wed 25 Apr | H | |
Aston Villa | |
15:00 | |||
| Sat 02 May | A | |
Tottenham Hotspur | |
15:00 | |||
| Sat 09 May | H | |
Queens Park Rangers | |
15:00 | |||
| Sat 16 May | A | |
Swansea City | |
15:00 | |||
| Sun 24 May | H | |
Southampton | |
15:00 |